BRIGHT 5040 Instruction Manual

1 INSTRUCTION MANUAL 5040 Wax Microtome/Quick Release Feather Blade Holder Serial No: 5560

2 INSTRUCTION MANUAL 1 SAFETY INFORMATION 3 Consumer Protection 3 Please Take Note Of The Following Warnings: 3 ELECTRICAL 3 OPERATION 4 ACCESSORIES 4 PRODUCT SAFETY SUGGESTIONS 4 DECONTAMINATION CERTIFICATES 4 IMPORTANT 4 WARRANTY 5 Optional Feedscrews 5040 7 1.2.3 QUICK RELEASE FEATHER BLADE HOLDER BLOCK 8 1.2.4 KNIFE CARRIAGE FEED CONTROL 8 1.2.4a FINE TRIM ADJUSTER / FTA (if fitted) 8 1.2.5 BLADE ANGLE 8 1.2.6 BLADE LOADING 8 1.2.7 SPECIMEN HOLDERS 8 1.2.8 SPECIMEN ORIENTATION (where fitted) 9 1.2.9 ADVANCE / REWIND CONTROL 9 1.2.10a LEFT HAND SIDE ADVANCE/REWIND CONTROL - /LHS (where fitted) 9 MOTOR DRIVE (where fitted) 9 FOOT SWITCH (where fitted) 10 1.2.11 SECTION COUNTER (where fitted) 10 1.2.12 MOTORISED ADVANCE / REWIND (where fitted) 10 1.2.13 OTHER ACCESSORIES 10 2. OPERATION 11 2.1 FITTING THE SPECIMEN 11 2.2 TRIMMING THE SPECIMEN 11 2.3 SECTION CUTTING AND COLLECTION 11 2.4 HINTS ON SECTIONING 11 3.1 DAILY CARE 12 3.2 MAINTENANCE & SERVICING 12 3.3 DECONTAMINATION 12 4. SPECIFICATION 12 ORDERING INFORMATION 14 OPTIONAL FEATURES 14 5. SPARE PARTS AND ACCESSORIES 15 5.2 5040 Electronics Spares List 17 5.3 Accessories and Consumables 18 A KNIFE SHARPENING SERVICE IS AVAILABLE - DETAILS ON REQUEST 18 MATERIAL SAFETY DATA SHEET 19 Name: CRYO-M-BED 19 MATERIAL SAFETY DATA SHEET 20 Name: CRYOSPRAY 20 MATERIAL SAFETY DATA SHEET 21 Name: LOW TEMPERATURE OIL 21 WARNINGS: Low Temperature 26 Knives / Blades 27 DECONTAMINATION CERTIFICATE 28 DECONTAMINATION PROCEDURES 29 QUALITY SURVEY REPORT 30

3 SAFETY INFORMATION Consumer Protection The Consumer Protection Act 1987 Part 1. refers to Product Liability. This legislation was issued as a direct result of an EC Directive to all member states and has been in force with effect from 1 March 1988. The Bright Instrument Company Limited, ever mindful of the need to ensure that their products are not subject to misuse and/or incorrect handling, have made it their aim to communicate any possible dangers to their customers. Whilst the Bright Instrument Company Limited markets products manufactured to the highest safety standards, it is in the interest of the purchaser that he is aware of the resultant dangers of misuse and/or incorrect handling of these products. Please Take Note Of The Following Warnings: ELECTRICAL a) Warning - A warning notice is fixed to the instrument (where applicable) stating that it should be disconnected from the mains supply before removing the panels. This warning should be strictly observed. b) Fuses – Fuse ratings are clearly indicated on all fuse panels adjacent to the fuse holder. If and when replacement is necessary, the correct fuse rating and type must be adhered to. c) Earthing (Grounding) – A protective earth terminal is fitted and must be used in all two-wire installations. MICROTOME KNIVES/BLADES The microtome knife/blade can be a hazard in the laboratory. Personnel should be made aware of the dangers and observe the following warnings: a) DO NOT leave the microtome unattended with an exposed knife/blade in position. Remove the knife/blade, or cover with the guards or visor provided. b) DO NOT leave unboxed knives/blades lying around. Place knives/blades that are not in use in their boxes or packets. c) DO NOT carry knives/blades unless secure in the box or packet provided. d) DO NOT clean the knife/blade along its length. Wipe the knife from the back edge to the cutting edge. e) REMEMBER that even used knives and blades are dangerous. The are still sharp and may have been used to cut potentially infectious specimens. f) DISPOSE of used knives and blades with the same care as other sharp objects. On no account should used knives or blades be placed in waste bins.

4 OPERATION When placing specimens in the microtome vice clamp jaws or holder, or carrying out manipulation, ensure the cutting hand wheel is locked with the head in the uppermost position, to minimise risks. LOW TEMPERATURES Low temperatures are present in cryostats and in freezing head stages attached to microtomes. On no account should you touch these cold surfaces without the use of gloves or sufficient clothing covering your exposed wrists/arms etc. touching cold surfaces can result in cold “burns” and permanent tissue and nerve damage. ACCESSORIES Fluids supplied as accessories with Bright instruments, such as Cryospray 134 and microtome oil are strictly for laboratory use only. They should not be taken by mouth and precautions afforded to other laboratory chemicals should be adhered to. PRODUCT SAFETY SUGGESTIONS All Bright Instrument Company Limited personnel are encouraged to make suggests regarding product safety. We also welcome such suggestions from our customers. They may be submitted by completing the appropriate (Safety) section of the Quality Survey Record Form supplied with all Bright instruments, or alternatively, by letter, telephone, fax or email. All communications should be direct to our Quality Assurance Department and will be acknowledged. DECONTAMINATION CERTIFICATES IMPORTANT If the instrument or any part of it is to be returned to Bright Instrument Company Limited, a decontamination certificate must accompany it, and please note the following: a) If the instrument or any part of it has been exposed to or been in contact with potential pathogenic or radioactive material, it is essential that it be decontaminated. Set procedures are laid down by the Health and Safety Executive for decontamination. For the avoidance of doubt, we ask that instruments or parts returned to us should be accompanied by a completed decontamination certificate. A copy of this can be found at the back of this instruction manual and we suggest you use a photocopy of this when returning parts. Alternatively we would be pleased to: b) either post or fax you another copy should you require. c) Should the instrument or any part of it be received in a condition that Bright Instrument Company Limited, consider to be a potential biological hazard, the instrument or part will be returned un-repaired at the expense of the customer. d) Overseas customers declarations must indicate that the package contains ‘British Returned Goods’. Failure to do so will involve customs duty payable by us, which will be invoiced to the sender.

5 WARRANTY The Warranty relating to the instrument is outlined in our Terms and Conditions of Sale paragraph 6. The Seller ‘s products are carefully inspected and submitted to its standard tests. The Seller warrants all its products to be free from defects in workmanship and materials under normal conditions of use and service provided always: a) that if any of the goods so manufactured is alleged to be defective in workmanship and material and is returned carriage paid, and protected against damage in transit to the Seller’s works at Huntingdon within 12 months from the date of despatch and if after examination by the Seller that goods or part of them are found to be so defective then the Seller will repair or replace them free of charge and will return them to the Buyer , carriage paid. b) where any part of the goods manufactured by the Seller is repaired or replaced under the terms of the foregoing warranty, such warranty shall thereafter be limited to a period of six months from the date when the goods shall have been re-delivered to the Buyer. c) this warranty does not apply to any defects caused by wear and tear, incorrect installation abnormal conditions of working, accident, misuse or neglect. d) That save as in this clause herein before expressed, the Seller shall not be under any liability for negligence or otherwise in respect of defects in goods delivered or for any injury, damage or loss resulting from such defects and the Seller’s liability under this clause shall be in lieu of any warranty or condition implied by law as to the quality or fitness for any particular purpose of such goods. e) This warranty is expressly in lieu of all other warranties, guarantees or liabilities expressed or implied by any of the Seller’s Representatives or Agents. Please see our separate Product Warranty sheet for deliveries to the mainland UK. WARNING Before proceeding to Operating Instructions, ensure you are familiar with the contents of the pages marked ‘Safety Information’. This instrument must only be used by competent persons.

6 OPERATING INSTRUCTIONS 1) INTRODUCTION The Bright 5040 is a rotary rocking microtome with specimen retraction on the return stroke. In standard form it can cut sections up to 60µm thick and will accept specimens up to 50 x 70mm. Suitable for paraffin wax and plastic embedded specimens, the microtome is fitted with a standard specimen vice clamp or a quick release holder for cassettes, A wide range of options and accessories are available, including motor drive and feed screws for cutting sections up to 300µm Knife/Blade guards are fitted to protect the operator from the knife/blade during normal operation. All controls are also placed clear of the knife/blade to permit all settings to be made in comfortable safety. 1.1 RECEIPT AND UNPACKING All packing must be carefully removed and parts checked against enclosed packing list. If any damage or discrepancy is noted, please inform our agent/distributor or Bright Instrument Company Limited immediately. 1.1.2 UNPACKING PROCEDURE The following should be followed when the instrument is received: a) At least two people are required during the unpacking. The microtome weighs 15Kg. b) Check that the outer packing is in good order and does not show signs of serious damage. c) Remove the microtome from the case and unpack it. d) Remove and unpack the accessories. FITTING THE CUTTING HAND WHEEL Push the hand wheel FIG 1(1) over the shaft on the side of the microtome. Ensure pin on shaft engages slot in centre of hand wheel, press home firmly then fit centre screw. 1.1.3 FITTING THE COARSE ADVANCE/REWIND CONTROL The rewind knob is fitted FIG 1(3) into the top of the microtome, ensuring it engages properly. 1.2 FEATURES Refer to FIGs 1 and 2. 1.2.1 CUTTING HAND WHEEL The hand wheel can be locked with the cutting arm in the upper position. Move the handle on the wheel to the top, pull the small lock knob FIG 1(2) and rotate it quarter of a turn, release and ensure it locates correctly. To operate the microtome, release the lock and turn the hand wheel in a clockwise direction. 1 3 FIG 1 2 4 5 6

7 1.2.2 THICKNESS CONTROL The knob FIG 1(5), on the front of the microtome, is used to set section thickness in µm. Simply turn the knob to the desired setting FEEDSCREWS A range of alternative feedscrews is available to cover section thickness’ from 0.2µm to 300µm. If one of these has been fitted in the factory, an appropriate scale of microns will also be fitted where available. However, if the user substitutes an alternative himself, the following table should be used to obtain the current section thickness. Optional Feedscrews 5040 Optional Feedscrews 5040 50256 manual 50256-1 MAR 50255 manual 50255-1 MAR 50257 manual 50257-1 MAR 50258 manual 50258-1 MAR 50259 manual 50259-1 MAR 50260 manual 50260-1 MAR “Thin Section” Standard in cryostat Standard in wax microtome 0.2 to 12µm 0.5 to 30µm 1 to 60 µm 2 to 120µm 3 to 180µm 5 to 300µm 0.2µm incrs. 0.5µm incrs. 1 µm incrs. 2µm incrs. 3µm incrs 5µm incrs. With scale With scale With scale Without scale Without scale Without scale Scale Markings: 2 5 10 20 30 50 4 10 20 40 60 100 6 15 30 60 90 150 8 20 40 80 120 200 10 25 50 100 150 250 12 30 60 120 180 300 Note: MAR = Motorised Advance/Rewind FIG 2 5040 QUICK RELEASE FEATHER BLADE HOLDER 1. Blade clamp lever 2. Blade angle locking lever 3. Blade angle indicator 4. Blade guard 5. Blade loading plate 6. Fixed blade guard 7. Blade guard knob 8. Blade clamping plate 9. Knife block clamp locking lever 1 2 3 4 5 6 6 7 9 8

8 1.2.3 QUICK RELEASE FEATHER BLADE HOLDER BLOCK The complete knife holder block FIG 1(6) can be moved towards or away from the specimen. Raise the knife block clamp locking lever FIG 2(9) on the right side of the knife holder and slide the holder to the desired position, or use knife carriage feed control. Note that the knife carriage feed control can be replaced by the FTA (Fine Trim Adjuster 1.2.4a) Press the lever down to lock. In normal paraffin was section cutting, the knife holder would seldom be moved once it has been put in the most convenient position for the size of the block. NB: The knife block clamp lever must be firmly locked during sectioning to prevent instability. 1.2.4 KNIFE CARRIAGE FEED CONTROL The knife carriage feed control FIG 1(4) on the centre front of the microtome moves the knife holder backwards or forwards once the knife lock clamp lever FIG 2(9) has been raised. This device permits incremented movements of the knife holder, for example, for trimming a specimen. 1.2.4a FINE TRIM ADJUSTER / FTA (if fitted) Works exactly the same as the knife carriage feed control 1.2.5 BLADE ANGLE Release the blade angle locking lever FIG 2(2) and taking the body of the blade holder in both hands, move it against the lower part of the assembly until the correct angle is shown on the blade angle indicator (3). Then re-lock the blade holder body with the blade angle locking lever. Nominally this angle should be set to 3º. 1.2.6 BLADE LOADING a. Move the blade guard to the lower position using the blade guard knob FIG 2(7). b. Unlock the blade clamping plate FIG 2(8) using the blade clamp lever FIG 2(1). c. Push the blade loading plate FIG 2 (5) to one side and very carefully place a new blade into position making sure that the blade is the correct way up. d. Slide the blade loading plate back to the centre of the assembly and use the blade clamp lever to lock the blade into position. Please note that as the blade wears it is possible to slide it to a new position by repeating this process and by doing this it is possible to utilise the whole length of the blade. 1.2.7 SPECIMEN HOLDERS 318 Quick Release Holder for wax cassettes The microtome is normally supplied with an orientating specimen holder with a specimen vice Alternatively, a cassette quick release holder may be fitted. To exchange specimen holders, simply unscrew the holder supplied from the orientating head. Some versions of the microtome are supplied with a fixed (non-orientating) specimen vice. In this case a cassette quick release holder can be clamped into this vice. Other types of specimen holders are available. FTA (Cryostat version)

9 1.2.8 SPECIMEN ORIENTATION (where fitted) To change the orientation of the specimen, first unlock the clamping lever, then either turn the adjusting knobs, or move the specimen holder by hand. NOTE: Before attempting to change the orientation ensure cutting hand wheel is locked. 1.2.9 ADVANCE / REWIND CONTROL The Advance / Rewind control (on top of the microtome) is used to advance the specimen to the knife and for trimming. It is also used to reset the mechanism usually after cutting each specimen. NOTE: the control cannot be rewound if the specimen is at the top of the cutting stroke; either lower the specimen or set the thickness control to 0µm to disengage the ratchet mechanism. A used feed indicator on the front of the microtome shows how much of the specimen-advance remains. Rewind the mechanism when the white pointer reaches the red zone, by turning the knob on top of the microtome clockwise, or if Motorised Advance / Rewind is fitted then see paragraph 1.2.13 1.2.10a LEFT HAND SIDE ADVANCE/REWIND CONTROL - /LHS (where fitted) The operation is exactly the same as for the Advance/Rewind control on the top of the microtome. Please note that this option is not available with Motorised Advance/Rewind 1.2.10 MOTOR DRIVE (where fitted) The motorised cutting system on the 5040 microtome is used for cutting large or hard specimens, and is also useful for serial sectioning. The system can be disengaged for manual cutting. 1. Ensure the specimen will not collide with the knife. 2. To engage motor drive, pull and turn hand wheel plunger knob. Then slowly rotate hand wheel until plunger engages. The hand wheel is locked in motor drive. See section 1.2.1 for manual use. 3. Switch on drive. The green power light will illuminate. 4. Select trim mode (for continuous running of motor drive) press start button (green) 5. Use the speed control to adjust cutting speed, when the head is in the cutting zone. 6. Adjust the zone control. The space between the upper and lower positions indicates that part of the specimen travel which is determined by the speed control. 7. By switching to single, the arm will be made to stop at the bottom of each stroke, allowing section collection. 8. To stop the drive, press stop. Start and stop functions can be used at any time. 9. The emergency-stop button stays in when pressed. Twist button in direction of arrows to release. Then press start to continue drive. LHS (Cryostat version)

10 FOOT SWITCH (where fitted) Plug the foot switch into the socket on the lower front surface of the motor drive control box. When the motor drive is in use, the left and right foot switches will duplicate the action of the stop and start buttons respectively. 1.2.11 SECTION COUNTER (where fitted) The section counter is used to pre-set the number of cutting stokes from 1 to 9,999 strokes. Press the buttons on the counter until the required number of sections is displayed, then press the reset button. For each cutting stroke the counter display will increase by one, giving the number of sections cut until it reaches the pre- set value when the red up light will illuminate and the drive will stop. To repeat the cycle, press the reset and start buttons. 1.2.12 MOTORISED ADVANCE / REWIND (where fitted) Do not operate the rewind motor when the cutting arm is in motion. Only operate the rewind motor with the cutting arm at the rest position. The advance motor may be operated when the cutting arm is in motion. Operating outside these parameters can cause damage to the mechanical components of the machine. MOTORISED SPECIMEN ADVANCE 1. Set the Specimen thickness control to 0µm 2. Fully rewind specimen, by pressing the rocker switch in the appropriate direction. 3. Adjust position of knife carriage with knife to specimen clearance set to a minimum. 4. Lock knife carriage. 5. Begin advance, with cutting arm fully up, by pressing and releasing ‘advance’ switch whilst rotating the hand wheel. The longer the switch is pressed the thicker the section. If ‘advance’ switch is pressed for more than 2 seconds, a faster advance of the specimen is achieved. MOTORISED SPECIMEN REWIND 1. Fully rewind specimen press ‘rewind’ switch for a minimum of 2 seconds and release. The feedscew will automatically stop when fully rewound. 2. To stop the specimen rewinding during the period, press ‘advance’ switch and release immediately. 3. For small rewind increments, press and quickly release ‘rewind’ switch. 1.2.13 OTHER ACCESSORIES Debris Tray: Use this tray to collect section trimmings etc: Alternative Feed Screws: See section 1.2.2 Instructions for fitting the alternative feed screws are supplied with the feed screws.

11 2. OPERATION 2.1 FITTING THE SPECIMEN Ensuring the cutting hand wheel is locked and the blade guard is covering the blade. Fit the specimen into the specimen holder. If the standard vice clamp is used, ensure the specimen is tightly clamped without damaging it. Alternatively, if the cassette quick release is used, care should be taken to ensure a close fit to the cassette. Remove all excess wax. Cassettes may be fitted vertically or horizontally. 2.2 TRIMMING THE SPECIMEN Release the knife block clamp locking lever FIG 2(9) and move the knife holder close to the specimen (see section 1.2.3) Re-lock the lever. Either set the section thickness control to thick sections, eg: 15-20µm (see section 1.2.2) and turn the hand wheel to trim the specimen. OR rotate/rock the hand wheel while using the coarse advance (see section 1.2.4) to trim the specimen. NOTE: If rocking the hand wheel, ensure trimming is done on the down stroke (hand wheel knob is 1 o’clock round to 5 o’clock position). Trimming on the upward (retraction) stroke will result in a subsequent very thick section and may damage the specimen. 2.3 SECTION CUTTING AND COLLECTION Select the desired section thickness. Turn the cutting hand wheel a few times to remove any surface roughness on the specimen block caused by trimming. Cut sections using slow, steady rotation of the hand wheel. Wax-embedded specimens should form a ribbon of sections on the blade. If the sections keep rolling then make sure that the wax blocks are still cool (+5ºC is the best temperature for most wax). If they continue to roll then try gently blowing down onto the knife to turn down the leading edge of the section. Sections can be removed either singularly or as a ribbon using forceps. Wax sections are usually floated onto warm water to soften and flatten them. They can be collected on microscope slides as follows: a. Dip a microscope slide vertically into the warm water some distance from the sections. b. Carefully bring the slide close to the section so that the sections edge contacts the slide in the appropriate position. c. Now raise the slide vertically from the water. 2.4 HINTS ON SECTIONING 1. Ensure the knife is sharp and clean. During use, the knife should be cleaned occasionally to remove a build-up of wax. Buff with a paper towel away from the edge of the knife. 2. Wax embedding specimens usually cut more easily if they have been chilled. It is common practice to trim a batch of wax blocks, then place them face down on a cold plate or crushed ice to cool them. This way they can be returned to the microtome and sections cut while they are still cold. 3. A slow, steady cutting action is needed to obtain the best results. However, different specimens may benefit from different cutting speeds, so experimentation will sometimes bring improved results. 4. If the section ribbon is excessively folded, creased or compressed on the knife, first float it onto cold water and flatten it with the aid of a small artist’s brush. Now collect sections with a microscope slide and carefully re-float onto warm water. 5. After collection, dry the wax sections onto the slides using either an oven or a hot plate. Using temperatures 10º-20º above the melting point of the wax. Sections will flatten and stick to the slide without being damaged. For more detailed instructions on the preparation, cutting and subsequent staining of paraffin wax sections, see any conventional text book of histological technique.

12 3. MAINTENANCE No routine maintenance is required. 3.1 DAILY CARE Empty section debris from the plastic debris tray. Brush away debris from around microtome. Ensure knife is kept sharp and free of nicks. No other daily attention is required. 3.2 MAINTENANCE & SERVICING The microtome requires no routine maintenance. In the event of problems, first refer to section 2.5. If no sections are being cut, ensure microtome feed has been rewound (see section 1.2.10). For advice on repairs, contact either Bright Instrument Co Ltd or your local representative, giving details of the fault and quoting the serial number of your instrument. 3.3 DECONTAMINATION It is the responsibility of the user to ensure that a decontamination procedure is employed which is appropriate to the nature of the work carried out. The 5040 Sledge Microtome is constructed of corrosion resistant materials, but hypochlorite (bleach) solutions are corrosive to many metals and should be avoided. 4. SPECIFICATION Construction Section thickness Range Specimen advance Knife block movement • Rotary rocking design of cast alloys, with detergent and solvent resistant epoxy-polyester finish • Standard range 1-60µm in 1µm steps for wax microtomes and 0.5-30µm in 0.5µm steps for the cryostat version. – See table below • Total specimen advance is 5600µm. • Total knife block movement is 44mm. Retraction • Approximately 50µm Cutting stroke • 56mm Specimen orientation • ± 8º horizontal and vertical (standard on 5040-01) Remaining feed Indicator • Visual display Knife holders • Standard knife holder accepts conventional steel knives; tungsten carbide tipped knives, glass knives and disposable blade holders. Alternatively, the quick release Feather blade holder is available as an optional feature either in addition to or in place of the standard knife holder block. Motorised section cutting • (Optional) With variable speed, variable cutting zone, single or continuous modes, hands off footswitch and emergency stop. Safety features • Counter-balance handwheel with safety lock. Integral knife guards, sliding both ways to cover knife edges • Dimensions • H300 x D500 x W300 • Net weight (manual): 20kg • Net weight (motorised): 30kg • Gross weight (manual): 25kg • Gross weight (motorised): 35kg • Shipping volume: 0.158m3 • Packing dimensions: H580 x D680 x W400mm • Note: Weights vary according to specification of instrument

13 OPTIONAL FEEDSCREWS 5040 Optional Feedscrews 5040 50256 manual 50256-1 MAR 50255 manual 50255-1 MAR 50257 manual 50257-1 MAR 50258 manual 50258-1 MAR 50259 manual 50259-1 MAR 50260 manual 50260-1 MAR “Thin Section” Standard in cryostat Standard in wax microtome 0.2 to 12µm 0.5 to 30µm 1 to 60 µm 2 to 120µm 3 to 180µm 5 to 300µm 0.2µm incrs. 0.5µm incrs. 1 µm incrs. 2µm incrs. 3µm incrs 5µm incrs. With scale With scale With scale Without scale Without scale Without scale Scale Markings: 2 5 10 20 30 50 4 10 20 40 60 100 6 15 30 60 90 150 8 20 40 80 120 200 10 25 50 100 150 250 12 30 60 120 180 300 Note: MAR = Motorised Advance/Rewind

14 ORDERING INFORMATION Order Code Description 5040-01 5040 Rotary Microtome with fine adjustment specimen orientation 5040-02 5040 Rotary Microtome without specimen orientation 5040-CV 5040 Rotary Microtome for cryostats OPTIONAL FEATURES Order Code Description 215 Knife carriage feed screw mechanism 217 Micro-adjustable knife angle mechanism 318 Quick release holder 53613 Supercassette quick release holder 225MR Robomatic motor drive for 220/240V AC, 50/60Hz 226MR Robomatic motor drive for 110/115V AC, 50/60Hz 225MR(S) Robomatic motor drive as 225MR but for very hard specimens 226MR(S) Robomatic motor drive as 226MR but for very hard specimens /C Electronic section counter /C(M) Mechanical section counter /V Foot switch for motor drive /Ma/r Motorised advance rewind /LHS Advance/rewind handle on left-hand side front /FTA Fine trim adjuster control /LC Cryostat type handwheel lock (not available with motor drive) 53430 Quick Release Feather Blade Holder 57903 Lever Release Feather Blade Holder

15 5. SPARE PARTS AND ACCESSORIES Parts can be obtained through your local Bright representative, or from Bright Instrument Co Ltd. When ordering parts, please provide the following details: a Model type and serial number of your instrument b Full description, part number and quantity of part(s) required c Address to which parts are to be delivered d Address to which invoice is to be sent 5.1 5040 Parts List Item Number Quantity Part Number Description 1 1 50384 Anti-roll assembly 2 1 50442 Knife clamp tie-bar 3 1 50431 Extension 4 4 50984 Knob 5 1 50983 Knob 6 1 50432 Adjusting screw 7 1 50399 Locating pin 8 2 50351 Knife clamp screw 9 3 50986 Knob 10 1 50406 Knife clamp, left hand 11 2 51344 Grub screw 12 1 52442 Knife guard assembly, left hand 13 2 52395 Lock screw 14 1 52355 Knife block 15 1 52443 Knife guard assembly, right hand 16 2 52203 Bush 17 1 52378 Push rod 18 1 52379 Push rod end 19 1 55000 Grub screw 20 1 50526 Knife angle pointer 21 4 55000 Grub screw 22 1 50410 Connecting crank 23 2 55600 PTFE washer 24 1 50357-2 Con rod assembly 25 1 50411 Crank pin 26 1 50407 Crank plate 27 1 50405 Knife clamp, right hand 28 1 50430 Clamp lever 29 1 50471 Stop pin 30 1 55001 Grub screw 31 1 50412 Pawl drive rod 32 1 50413 Pawl pivot 33 1 50414 Pawl spring 34 1 52439 Pawl 35 1 52380 Push rod holder 36 2 55241 Cap head screw 37 2 55616 Washer 38 1 55104 Cap head screw 39 1 55003 Grub screw 40 1 52390 Top arm pivot pin 41 1 52372 Pivot arm rod 42 1 50255 Feed screw assembly 43 1 50404 Bearing post 44 1 50416 Thickness plate 45 1 50459 Knock off arm 46 2 55601 Ball 47 5 55101 Cap head screw 48 1 50458 Retaining plate 49 1 50457 Spring plate 50 1 52371 Pivot arm adaptor 51 1 55610 Washer 52 1 50476 Clamp plate 53 1 50450 Locating pin 54 1 50449 Vee block 55 1 50353 Vice clamp screw 56 2 52427 Blind clamp spring 57 2 52427 Top blind clamp 58 2 53428 Top blind clamp screw 59 1 50987 Rewind knob 60 1 55222 CSK SLTD screw 61 1 50363 Rewind handle 62 1 52348 Top arm (std) 63 1 55108 Cap head screw 64 2 50370 Spring anchor pin 65 1 55621 Washer 66 1 55627 Double coil washer 67 6 50510 Anti rattle body 68 1 50453-1 Pivot arm 69 1 50372 Stop spacer 70 2 55105 Cap head screw 71 8 50423 Anti rattle joint 72 1 50375 Retraction link rod 73 28 55100 Cap head screw 74 3 50438 Retaining plate 75 1 50447 Main hinge

16 76 1 50373 Stop pin 77 1 50454-1 Hinge segment 78 4 50445 Small hinge 79 8 50446 Retaining plate 80 3 56725 Full nut 81 1 55626 Crinkle washer 82 1 50475 Washer 83 1 50507 Anti-rattle body 84 1 55234 Pan head screw 85 1 50451 Pawl arm 86 2 50980 Click block spring 87 2 51443 Click ball 88 1 50417 Thickness block 89 2 55111 Btn head screw 90 2 50991 Pawl arm bearing 91 2 50475 Pawl washer 92 2 51058 Main shaft brush 93 1 56402 Circlip 94 2 55001 Grub screw 95 1 52430 Main drive shaft 96 1 52345 Base 97 2 55241 Cap head screw 98 1 52357 Bearing holder 99 4 52202 Bush 100 1 52361 Thickness collar 101 2 52360 Thickness gear 102 1 52359 Thickness shaft 103 2 52387 Knife block runners 104 1 56700 Thickness pointer 105 1 52358 Thickness knob shaft 106 1 52356 Bearing holder 107 2 55120 Cap head screw 108 3 51443 Ball plunger 109 2 55003 Grub screw 110 1 52362 Thickness ring holder 111 1 52370 Thickness knob 112 1 52363 Thickness ring (std) 113 1 50387 Knob 114 1 52441 Locating pin 115 1 50388 Bearing holder 116 1 50389 Bush 117 1 56403 Circlip 118 1 50392 Leadscrew 119 1 52389 Clamp bolt 120 2 51344 Grub screw 121 1 50378 Lock screw 122 2 50386 Bearing post 123 1 50419 Centre spindle 124 2 55002 Grub screw 125 1 50443 Thickness crank arm 126 1 52388 Knife carriage block 127 2 55508 Nut 128 1 52386 Thickness drive rod 129 1 55105 Cap head screw 130 1 50402 Clamp plate 131 1 52411 Retraction roller 132 1 50401 Retraction roller pin 133 2 50371 Spring 134 2 56725 Nut 135 1 55628 Double coil washer 136 2 50403 Retraction plate 137 2 50376 Spring anchor pin 138 1 50374 Pivot stud 139 4 50391 Plastic feet 140 1 52373 Pivot rod adaptor 141 1 52374 Pivot rod 142 1 52375 Pivot 143 1 55001 Grub screw 144 2 52437 Bush 145 1 52376 Pivot block 146 1 55001 Grub screw 147 1 52377 Pivot rod end 148 1 55106 Cap head screw 149 1 55620 Washer 150 2 55104 Cap head screw 151 1 55630 Washer 152 1 50493 Bottom washer 153 1 50493-1 Spring

17 5.2 5040 Electronics Spares List Part Number Description 52471 5040 control box for wax version 52472 5040 control box top 52474 Facia panel (blank with rewind) 52473-1 acia panel (rewind 230V 0.5AT printed) 52473-2 acia panel (rewind 115V 1.0AT printed) 52474 Facia panel (blank no rewind) 52474-1 acia panel (no rewind 230V 0.5AT printed) 52474-2 acia panel (no rewind 115V 1.0AT printed) Earth stud 4mm Earth bolt c/s 137043-02 Ring crimp 4mm 134024 Bridge rectifier P1620F 133078 Flex bushing 132106-17 Capacitor RAD 4700MF/40V 133016 Capacitor clip 133064 Feet, rubber grey 138404-19 Fuse 22mm 2.0AT 138404-16 Fuse 22mm 1.0AT 133034 Fuseholder 22mm panel 134028 Lamp, neon green 136002 Motor drive board 136017 Slider board 52339 Slider knob 130200-61 Resistor 0.25W, 100K 137031 Socket IEE for 1 amp 137031 Socket IEE for 1 amp 137023 Socket DIN 5 way 60 deg 137025-02 Socket Dee 15 way 137013-09 Housing Molex 10 way 0.1 137013-14 Housing Molex 15 way 0.1 137013-18 Crimp kk0.1 137013-19 Polarising key 138016 Switch SP rocker 138114-01 Switch emergency stop 138114-03 Sw Em stop contact block 138118-01 Push switch green mom 138118-02 Push switch red mom 137042-15 Receptacle red 1/4 inch 133022-03 Terminal block 138014 Transformer 75 Va 131105 Coiled coil 6 amp 139025 Motor-DC, 36 V/3000 RPM 137026-02 Plug dee 15 way 137027-02 Shell for dee 15 130403 Servopot 6657S-1-103 Additional Items for /C and /C(M) 139096-01 Counter 139096-02 Connector 139096-03 Fixing plate 137013-04 Plug 5 pin molex 137013-18 Crimp 130200-41 Resistor 0.25W 2k2 130200-49 Resistor 0.25W 10k0 Additional Items for /Ma/r 138103 Motor(s), PF55-44C 138075-00 Micro sw CHERRY DC2 138075-01 Micro sw lever short 139089 Advance/rewind board 138004-05 Relay 24V DPCO 138004-02 Relay socket 137013-04 Housing 5MX 0.1 137013-18 Crimp 137017-09 Housing 10MX 0.156 137017-18 Crimp 138117-01 Switch centre off mom 138117-02 Switch lever black 138117-03 Switch bezel black Additional Items for /V 137024 Plug free DIN 138026 Twin footswitch Additional Items for Microtome Light 138034-02 Ballast 8W/115V 138034-01 Ballast 8W/230V 137032 Plug IEE straight 138017 Lamp assembly 2 x 4W 138018 Magnifier

18 5.3 Accessories and Consumables Part Number Description /R Conveyor for section ribbon. 50539 Orientating object holder, with fine adjustment screws, factory fitted. 50657 Orientating object holder, without fine adjustment screws, factory fitted. 51637 Quick release hardboard holder, without orientation, for 5040-02. 51637-1 Quick release hardboard holder, with orientation, for 5040-01. 50533 Quick release wax cassette holder, without orientation, for 5040-02. 50209 Triangular glass knife holder, fixed. 50681 Triangular glass knife holder, orientating. These accept 25mm high Latta-Hartmann knives with edges up to 15mm. 52985 CO2 (gas) object holder and knife freezer. 50208 Sloped (20º) knife holder. 50213 Ralph knife holder. 50214 Ralph knife holder with section float-out trough. For long edged glass knives with edges up to 38mm. 52987 Illuminated magnifier. 50230 Standard knife with box, C-profile, 189 x 27 x 10mm. 22º angle, tapped to accept holder for Shandon knife sharpener, safety cut-outs at each end. 50724 Knife sharpening back for 50230. 50232-1 hardened steel knife with box, C-profile, 160 x 35 x 9mm. 15º angle, suitable for large area sections. 50210 Knife sharpening back for 50232-1. 50207 Steel knife with box, C-profile, 160 x 32 x 13mm. 23º. 50211 Knife sharpening back for 50207. 51675 Handle for 50230, 50232-1 and 50207. 50234 Tungsten carbide tipped knife with box, 228 x 38 x 6mm. Suitable for cutting bone and hard plastics. NB: needs to be resharpened at our factory. 52647 Stem for 50232-1 and 50234 knives. 52671 Knife sharpening kit. Includes hone, strop, oil, three grades of abrasive and instructions. 57612 Coarse abrasive, 6g net. 57611 Fine abrasive, 6g net. 57610 Honing compound, 6g net. 50239 Clock oil, 6g net. 50140 ‘Magnacut’ disposable blade system. Consists of magnetic blade holder, 50mm anti-roll plate, 10 blades, blade removal tool, micro-adjusting T-piece and stem, box and instructions. 50133 ‘Magnacut’ disposable blade system. Consists of magnetic blade holder, Magnaplate anti-roll plate, 10 blades, blade removal tool, box and instructions. 50540 ‘Magnacut’ disposable blade holder only. 52727 Long-life disposable blades for Magnacut, C-profile, pack of 50. 51564 ‘Magnacut’ blade removing tool. 50240 Feather blade holder with box. 50241 Feather disposable blades, pack of 50. A KNIFE SHARPENING SERVICE IS AVAILABLE - DETAILS ON REQUEST 50260 5 - 300µm feed screw. 50259 3 - 180µm feed screw. 50258 2 - 120µm feed screw. 50257 1 - 60µm feed screw. 50255 0.5 - 30µm feed screw. 50256 0.2 - 12µm feed screw. 50259-1 3 - 180µm feed screw for /Ma/r option. 50258-1 2 - 120µm feed screw for /Ma/r option. 50257-1 1 - 60µm feed screw for /Ma/r option. 50255-1 0.5 - 30µm feed screw for Ma/r option. 50256-1 0.2 - 12µm feed screw for /Ma/r option. 50734-1 Object holder, 22mm diameter, solid. 50734-2 Object holder, 22mm diameter, solid - as 50734-1 but long type. 50735-1 Object holder, 37mm diameter, solid 50735-2 Object holder, 37mm diameter, solid - as 50735-1 but long type. 50744 Object holder, 5mm diameter, solid. 50721 Object holder, 50mm diameter. 50741 Object holder, 50 x 50mm. 50743 Object holder, 50 x 70mm. 50221 Quick release object holder clamp, complete with 50 metal object discs. 50690 Metal object holder discs, 22mm, pack of 50. 50204 Cork object holder discs, 22mm, pack of 50. 50204-1 Cork object holder discs, 50 x 50mm, pack of 50. 50162 Adaptor, to accept Ames cryostat, saddle type object holders. 52658 Vertical vice clamp. 57713-1 Bright Cryospray 134, 300ml aerosol can. 57713 Bright Cryospray 134, 300ml aerosol can, carton of 12 cans. 54791 Low temperature oil, 200ml bottle. 54791-1 Low temperature oil, 4.54 litre drum. 57344 Knife cleaning brush. 57808 Anti static brush, 12mm. 52531 Wax brush and debris tray. 53573 Spare fuse set for 5040-001 or 5040-002 with 225MR. 53574 Spare fuse set for 5040-001 or 5040-002 with 226MR.

19 MATERIAL SAFETY DATA SHEET Name: CRYO-M-BED Part Number: 53581 Product Information By: Bright Instrument Company Limited Address: St Margaret’s Way, Huntingdon, Cambs, PE29 6EU, England Telephone: 01480 454 528 / 451 499 / 451 980 Emergency: 999 Fax: 01480 456 031 Email: [email protected] Trade/Type: EMBEDDING COMPOUND Container: Disposable plastic bottles Uses: Embedding compound for frozen tissue specimens Data Sheet: 3 Description: Colourless viscous liquid Information on Ingredients Physical and Chemical Properties Blend of polyviol alcohol 217, thymol and water Colourless viscous liquid Hazards Identification: Stability and Reactivity Skin: Can cause skin irritation May react with oxidising materials Respiratory: May cause difficulty in breathing if exposed to very high concentration Ingest: May be harmful by ingestion Eyes: Eye irritation First Aid procedures Toxicoloigical Information Skin: Wash thoroughly, with soap and water No harmful effects if handled correctly. May give off toxic fumes in the case of fire Respiratory: Move to fresh air Ingest: Rinse mouth out with water, in sever cases seek medical attention Eyes: Flush copiously for at least 15 minutes Fire Fighting Measures Ecological Information Hazards: May cause toxic fumes Degradable, miscible in all proportions Equipment: Water spray, foam, dry powder, Co2 Accidental Release Measures Disposal Considerations Spill: Absorb on an inert absorbent, bag and arrange disposal. Wash area in water and detergent Waste: Bag and dispose of in accordance with local authority requirements Handling and Storage Transport Information Special Requirements: NONE No restrictions Exposure Controls Regulatory Information OES: Not assigned (long term, 8 hour TWA) NONE Skin: Avoid contact Respiratory: Avoid very high concentrations Ingest: Do not eat, drink or smoke Eyes: Goggles should be worn Additional Information/Comments: Information given is, to the best of the Company’s knowledge and belief, accurate and reliable. However, no warranty, guarantee or representation is made to it’s accuracy, reliability of completeness. Issue 6 /June 2000 - Last reviewed: June 2004 /Next review: June 2006

20 MATERIAL SAFETY DATA SHEET Name: CRYOSPRAY Part Number: 57713 Product Information By: Bright Instrument Company Limited Address: St Margaret’s Way, Huntingdon, Cambs, PE29 6EU, England Telephone: 01480 454 528 / 451 499 / 451 980 Emergency: 999 Fax: 01480 456 031 Email: [email protected] Trade/Type: Bright Cryospray 134 Aerosol Freezing Agent Container: Aerosol Uses: Rapid Freezing of tissue specimens to –52ºC Data Sheet: 48 Description: Colourless viscous liquid Information on Ingredients Physical and Chemical Properties 1, 1, 1, 2 – Tetrafluoroethane – contents 80-100% Appearance: Aerosol Odour: Characteristic Hazards Identification: Stability and Reactivity May cause frost bite if intentionally misused Avoid powdered metal, alkali metals alkali earth metals Avoid heat, flames and other sources of ignition First Aid procedures Toxicoloigical Information Skin: Wash thoroughly, with soap and water May cause frost bite if intentionally misused No harmful effect if handled correctly. May give off toxic fumes in the case of fire Respiratory: Provide rest, warmth and fresh air If discomfort continues, seek medical attention Ingest: Rinse mouth out with water, in sever cases seek medical attention Eyes: Flush copiously for at least 15 minutes SEEK MEDICAL ADVICE Fire Fighting Measures Ecological Information This product is not classed as flammable under current regulations. Special Fire Fighting Procedures : use water to keep fire exposed containers cool and disperse vapours. Breathing apparatus should be worn if exposure of fumes s likely. Unusual Fire Explosion Hazards: Possible risk of can rupture when exposed to fire/high temperatures. Hazardous Decomposition Products: Fire or high temperatures create halogenated hydrocarbons, oxides of carbon Water Hazard Classification: Discharge of product will enter the atmosphere and will not result I long term aqueous contamination Global Warming Potential: 0.28 (R11=1) (1,1,1,2 – Tetrafluorethane) Ozone Depletion Potential 0 (R11=1) (1,1,1,2 – Tetrafluorethane) Accidental Release Measures Disposal Considerations Spill: Let evaporate and ventilate area well Waste: DO NOT pierce or burn empty cans. Dispose of in accordance with local authority requirements. Handling and Storage Transport Information Usage Precautions: CAUTION pressurised container DO NOT expose to temperatures exceeding 50ºC DO NOT puncture or incinerate even when empty DO NOT spray onto naked flame or any incandescent material Spray in short bursts to prevent cooling of the can STORAGE PRECAUTIONS: Store in a cool dry place, away from all sources of heat, including direct sunlight Road: UN No.1950 CEFUC TEC (R) No.20G26-1 ADR Class 2 ADR ITEM No.5A Air: UN Air No.1950 Air Transport Class 2 Sea: UN Sea No.1950 Sea Transport Class No.2 IMDG Page No.2102 Exposure Controls Regulatory Information 1,1,1,2 – Tetrafluoroethane (HFC 134a) OED: Long term exp (8hours TWA ref period) 1000ppm (rec)/4240mg/m3 Skin: Avoid contact, it is advised to wear gloves Respiratory: Good ventilation required if used in confined space Ingest: Do not eat, drink or smoke Eyes: Wear goggles during use if there is any risk of eye contact, but not generally required under normal use. CHIP: S23 DO NOT breathe gas/fumes/vapour/spray CHIP: S24/S25 Avoid contact with skin and eyes CHIP: S51 use only in well ventilated areas COSHH Regulations 1999 Additional Information/Comments: Information given is, to the best of the Company’s knowledge and belief, accurate and reliable. However, no warranty, guarantee or representation is made to it’s accuracy, reliability of completeness. Issue 7 /January 2004 - Last reviewed: May 2004 /Next review: May 2006

21 MATERIAL SAFETY DATA SHEET Name: LOW TEMPERATURE OIL Part Number: 57491 Product Information By: Bright Instrument Company Limited Address: St Margaret’s Way, Huntingdon, Cambs, PE29 6EU, England Telephone: 01480 454 528 / 451 499 / 451 980 Emergency: 999 Fax: 01480 456 031 Email: [email protected] Trade/Type: CLAVUS OIL 15 Container: Plastic Bottle Uses: For lubrication of microtomes and remote control spindles Data Sheet: 44 Description: Low temperature oil Information on Ingredients Physical and Chemical Properties Mineral oil Physical form: Liquid Density: @15ºC, Kg/1 0.878 Odour: Mineral oil odour Colour: Pale amber Flashpoint: 153ºC (IP 34PM closed cup) Hazards Identification: Stability and Reactivity This product is NOT classified as dangerous for supply or conveyance Stable: Yes Conditions to Avoid: Extreme temperatures store between 0 – 50ºC Materials to Avoid: Strong oxidising agents Hazardous Decomposition/Combustion Products: Dependant of conditions bringing abut decomposition the following substance may be expected from normal combustion: carbon dioxide – polyeyelic Aromatic Hydrocarbons, carbon monoxide – Unburnt hydrocarbons, water – unidentified organic and inorganic compounds, particulate matter – nitrogen oxides First Aid procedures Toxicoloigical Information Skin: Wash thoroughly, with soap and water Health effects: EYES: May cause transient irritation. SKIN: Unlikely to irritate on brief or occasional exposure INHALATION: Low volatility make inhalation unlikely at ambient temperatures. INGESTION: Possible aspiration into the lungs with possible resultant chemically induced neumonia OTHER: NONE known Respiratory: Remove from exposure Ingest: DO NOT induce vomiting. Wash out mouth with water, SEEK MEDICAL ATTENTION URGENTLY Eyes: Flush copiously for at least 15 minutes. If irritation persists SEEK MEDICAL ADVISE Fire Fighting Measures Ecological Information FIRE: Extinguish fires with foam, dry powder, CO2 or water fog - do not use water jets Soil: Will biodegrade Water: Will not evaporate or dissolve Air: Nil DO NOT allow to enter drainage systems, rivers or waterways Accidental Release Measures Disposal Considerations Spill: Avoid entry into drains and waterways, spilt product will present a slip hazard Waste: Dispose of in accordance with local authority requirements Handling and Storage Transport Information Handling: Storage: No special requirements Store away from direct heat and avoid extremes of temperature, DO not leave container unsealed Not classified as dangerous to transport Exposure Controls Regulatory Information 5mg/m3 (8hour TWA) and 10mg/m£ (15 minute reference period) (Ref:EH40/1999) This product is a preparation and is NOT classified according to EEC Guideline Additional Information/Comments: Information given is, to the best of the Company’s knowledge and belief, accurate and reliable. However, no warranty, guarantee or representation is made to it’s accuracy, reliability of completeness. Issue 2 /March 2000 - Last reviewed: March 2004 /Next review: March 2006

22 SAFETY WARNING Low temperatures are present in this equipment. Extreme care should be taken. DO NOT let bare skin come into contact with metal surfaces

23 SAFETY WARNING EXTREMELY SHARP KNIVES / BLADES USE KNIFE / BLADE GUARDS AT ALL TIMES USE CORRECT TOOLS FOR REMOVAL AND INSERTION OF KNIVES / BLADES DO NOT LEAVE KNIVES / BLADES LAYING AROUND PLACE KNIVES / BLADES NOT IN USE, INTO BOX / WALLET PROVIDED

24 QA028/ISSUE5/OCT00(F003) HEALTH AND SAFETY AT WORK ACT DECONTAMINATION CERTIFICATE Any product which is to be returned to Bright Instrument Company Limited or serviced on site, must be cleaned and decontaminated in the appropriate manner. This certificate, duly completed, must be either sent in advance (fixed to the outer packing containing the product), or handed to the service engineer. Packages will not be opened nor servicing commenced until the Company or service engineer have received a satisfactory certificate. Should returned goods be considered a hazard by the Company, they will be returned immediately to the customer at his/her expense. NB: Microtome knives must be in boxes. Description: Product Code: Serial Number: Order Number: Quantity: Tick Box A if applicable. Otherwise complete all parts of B, providing further information as requested or appropriate. A  This equipment has not been in contact with unfixed biological samples. B1. This equipment has been exposed internally or externally to hazardous materials as indicated below: YES/NO Blood, body fluids, pathological samples Provide further details here: YES/NO Other biohazards YES/NO Chemicals/substances hazardous to health YES/NO Other hazards 2. This equipment has been cleaned and decontaminated: YES/NO If YES, give details of the methods: Provide further details here: If NO*, please indicate why not: * Such equipment must not be returned without the written agreement of Bright Instrument Company Limited. 3. The equipment has been prepared to ensure safe handling/transportation. YES/NO Signed: Institute: Department: Address: Name: Postcode: Position: Telephone: Extn: Date: Facsimile:

25 DECONTAMINATION PROCEDURES Cryostats & Ultra Low Temperature Freezing Units If decontamination is required carry out the standard procedures as practised in your laboratory. It is the responsibility of the customer to use a decontamination procedure appropriate to his/her work. The following decontamination method is as recommended in the ‘Code of Practise for the Prevention of Infection in Clinical Laboratories and Post-mortem Rooms’, ISBN 0 11 320464 7. 1 Bring the cryostat to room temperature. 2 Place 50-100ml of formalin BP in a flat dish inside the chamber. Close the window. 3 Leave for at least 24 hours, preferably 48 hours. 4 Open the window and place a beaker containing 10ml of ammonia SG.880 in the chamber. Close the window. 5 Leave for one hour. The cryostat is now decontaminated. Microtomes If decontamination is required carry out the standard procedures as practised in your laboratory. It is the responsibility of the customer to use a decontamination procedure appropriate to his/her work. Microtome Knives If decontamination is required carry out the standard procedures as practised in your laboratory. It is the responsibility of the customer to use a decontamination procedure appropriate to his/her work. For further information regarding alternative decontamination procedures please refer to ‘Safe Working and the Prevention of Infection in Clinical Laboratories’, ISBN 0 11 885446 1.

26 QA023/ISSUE 4/AUG99(F018) QUALITY SURVEY REPORT Our watchword is QUALITY. In our continuing endeavour to improve the quality and performance of our processes and products, we would welcome any initial comments on the following aspects of our service and products. As you have only just received the product we do not feel that you could asses the actual workings of the instrument accurately, so we will follow up in approximately six months with a Customer Feedback – Voice of the Customer questionnaire. If, of course, you have any comments to make prior to receiving the questionnaire, please feel free to contact us. Please return this form either by post or by fax on 01480-456031, for the attention of the QA Manager. Model: Serial Number: Institute: Department: Address: Postcode: Telephone: Extension: Aspect Comments and Suggestions Purchasing: Did the purchasing process run smoothly with respect to our involvement? e.g. correct advice, lead times, payment arrangements etc. Delivery: Was the instrument in a satisfactory condition on arrival? Installation: Did we install the instrument? If so was adequate pre-use instruction given? User information: Did you receive an operating manual? Do you believe it is comprehensive enough for your use? Safety: Any comments? Miscellaneous: Any other aspect you would like to comment on, e.g. appearance, first impressions etc. Signed:………………….…………….…. Name:………………………..….…..……. Position:……….……….……………..……. Thank you for helping us to help you in the future