Biotage Flash 400 Operation & User’s Manual

Contents Biotage ® Flash 400 User Manual CONTENTS 1 Introduction 1 Speed 1 Safety 1 Performance 2 Description and Specifications 2 Biotage ® Flash 400 Frame 2 Radial Compression Module 4 Biotage ® Flash 400 Prepacked Cartridge 4 Radial Compression Fluid Reservoir 5 Control Panel 6 Side Connecti ...

on prepacked cartridge technology that provides users of traditional self-packed glass columns with three critical operational benefits: speed, safety, and performance. Speed Unlike glass columns, which operate at low pressure and have very poor flow distribution, Biotage f ...

Description and Specifications Description and Specifications Figure 2 A B C E H I G D . Flash 400 system. A = hoist, B = hoist control box, C = cartridge tool, D = prepacked cartridge, E = radial compression module, F = radial compression fluid reservoir, G = control panel, H = solvent inlets and fraction ...

O-Ring Material Composition Type Solvent Polarity Solvent Viton EPDM (Ethylene Propylene) Chemraz Normal Phase 0.1 Hexane Good Poor Good 2.4 Toluene Fair Poor Good 2.5 MTBE Poor Poor Good 3.1 DCM Fair Fair Good 3.9 IPA Good Good Good 4.0 THF Poor Poor Good 4.4 Ethyl Acetate Poor Good Good 5.1 Methanol Poor Good Good Reversed ...

Description and Specifications Top Head Assembly Valves The top head assembly has the following valves. Valve Description MV-02 Three-way injection valve. Selects the solvent or sample inlet (see Figure 4). During cartridge removal, compressed gas may be blown through this valve and through the cartridge t ...

Control Panel The system includes a control panel with the following pressure gauges and valves required to operate the system. Label Description PG-01 Pump pressure gauge. Monitors the solvent pump (P-01) outlet pressure. PG-02 Cartridge compression pressure gauge. Monitors the pressure inside the radial compression module. ...

Description and Specifications Hoist The hoist (see A in Figure 2 on page 2) is used to move and seal the top head assembly, insert and remove cartridges, and when necessary, move the radial compression barrel. The maximum working load is 125 kg (275 lbs). The hoist is pneumatically operated and has a sepa ...

Ensure that the cartridge tool cannot be moved within the cartridge top. If the tool can be moved, loosen the knurled knob and repeat the tightening process to re-engage. Move the hoist arm so that the safety hook is centered over the cartridge tool and then fasten the hook to the tool’s eyebolt. Head Sling Assembly The hea ...

Description and Specifications System Dimensions and Valves, Gauges, and Regulators All valves used on the Flash 400 system are fabricated from 316 stainless steel with a PTFE seat and rated by the manufacturer to at least 200% of the maximum system working pressure. The pressure gauges operate in contact ...